Project Description:

The high number of diabetics in Indonesia, who also experience chronic wounds such as diabetic ulcers, provides high needs for the development of chronic wound care products. Utilization of nyamplung oil, which is a local natural resource as a candidate active substance for diabetic ulcers, show promising potential due to the antibacterial activity, its role in the inflammatory process, and its activity in inducing proliferation of fibroblasts and keratinocytes. This research is expected to be a proof-of-principle experiment of the use of BC-keratin matrix as a primary dressing, which has been pre-clinically proven to be an effective wound exudate and supports the process of skin remodeling for optimal wound healing in diabetic ulcer patients.